|
Symbol Name ID |
Il12b
interleukin 12b MGI:96540 |
| Darker colors indicate more annotations |
| Human Phenotypes | Immunodeficiency |
Asthma |
BCGitis |
| Disease(s) Associated with IL12B | |||
| asthma | |||
| immunodeficiency 29 |
| Mouse Phenotypes | abnormal granulocyte physiology |
abnormal lymphocyte physiology |
abnormal NK cell physiology |
impaired natural killer cell mediated cytotoxicity |
abnormal CD4-positive, alpha-beta T cell physiology |
abnormal T-helper 1 physiology |
abnormal CD8-positive, alpha-beta T cell physiology |
abnormal macrophage physiology |
decreased circulating interferon-gamma level |
decreased susceptibility to type IV hypersensitivity reaction |
decreased interferon-gamma secretion |
decreased interleukin-17 secretion |
increased susceptibility to bacterial infection |
increased susceptibility to bacterial infection induced morbidity/mortality |
increased susceptibility to parasitic infection |
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| Availability | Mouse Genotype | |||||||||||||||
| Il12btm1Jm/Il12btm1Jm | ||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/30/2024 MGI 6.23 |
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